The potential health benefits of resveratrol may be due to is ability to activatethe powerful fat controlling hormone adiponectin.
By Nathan Gray
The potential health benefits of resveratrol may be due to is ability to activatethe powerful fat controlling hormone adiponectin, according to a new study.
Researchers from the University of Texas found that the antioxidant compound resveratrol stimulates the expression of adiponectin – a hormone released from fat cells, which plays an important role in the regulation of insulin sensitivity and energy
The new study, published in the Journal of Biological Chemistry, reports that resveratrol stimulates the expression and protein clustering (multimerization) of adiponectin in specialized fat cells through the activation of a protein known as disulfide bond-A oxidoreductase- like protein (DsbA-L).
“Our study uncovers a novel mechanism by which resveratrol exerts its health beneficial effect,” said senior author Dr Feng Liu, professor of pharmacology at UT.
“The results from these studies should be of interest to those who are obese, diabetic and growing older,” he added.
They said the finding that resveratrol promotes adiponectin expression provides a novel mechanism by which resveratrol exerts its health beneficial functions.
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