Fat cells may play an important role in mediating the anti-obesity effects of omega-3 rich fish oils, according to a new review.
The review, published in The Journal of Nutritional Biochemistry, suggests that omega-3 fatty acids promote changes in fat tissue (adipose tissue) metabolism, which may bring about changes in cellular signaling and secretion, contributing to improvements in glucose and lipid metabolism.
“It has been well established that adipose tissue not only is an inert storage organ but also secretes many bioactive substances,” said the authors, led by Dr Michael Puglisi from Vanderbilt University, USA.
“Various reports indicate that improved adipose (AT) tissue storage and secretory functions and a reduction in AT-specific inflammation have a central role in mediating the beneficial effects of fish oil against the risk factors of metabolic syndrome” added the reviewers.
Commenting independently, Harry Rice, PhD, V.P regulatory & scientific affairs for the omega-3 trade association GOED (Global Organization for EPA and DHA Omega-3s) told NutraIngredients that the study provided a “well-done, not to mention, much needed review of the existing gaps in the area.”
Rice explained that although there is still a lot that is unknown with regard to the mechanisms of the omega-3 response; based on the information in the current review, he “can’t help but believe that we will likely see some beneficial pharmacological agents emerge in the very near future.”
Read article
© Natural Factors. All rights reserved.